Colistin sulfatePh. Eur.

(Polymyxin E sulfate)
C53H104N16O21S2 Mr 1365.6CAS [1264-72-8]

Peptide antibiotic. Mixture of the sulfates of polypeptides produced by certain strains of Bacillus polymyxa var. colistinus. Acts mainly against gram negative bacteria. Causes changes in membrane structure resulting in leakage of small molecules. Soluble in water; stable between pH 2 - 6 at 4 °C. Protect from light.


Assay (HPLC)
(sum of polymyxins E1, E2, E3, E1 - I and E1 -7 MOA)
min. 77.0 %


References:
  1. Storm, D.R. et al. (1977) Ann. Rev. Biochem. 46, 723-63
DANGER
Hazard Statements H301
Precautions P264 - P270
Reaction P301 +P310 - P330
Storage P405 - P501

GGVSE/ADR: 6.1 III UN2811IATA: 6.1 III UN2811EINECS: 215-034-3WGK: 1HS: 29419000
Storage Temperature: +2 °C to +8 °C

Cat.No.
Size
EUR
17420.01
250 mg
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H301

Deutsch:

Giftig bei Verschlucken.

English:

Toxic if swallowed.

Français:

Toxique en cas d'ingestion.

Italiano:

Tossico se ingerito.

Español:

Tóxico en caso de ingestión.

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P264

Deutsch:

Nach Gebrauch … gründlich waschen.

English:

Wash … thoroughly after handling.

Français:

Se laver … soigneusement après manipulation.

Italiano:

Lavare accuratamente … dopo l’uso.

Español:

Lavarse … concienzudamente tras la manipulación.

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P270

Deutsch:

Bei Gebrauch nicht essen, trinken oder rauchen.

English:

Do no eat, drink or smoke when using this product.

Français:

Ne pas manger, boire ou fumer en manipulant ce produit.

Italiano:

Non mangiare, né bere, né fumare durante l’uso.

Español:

No comer, beber ni fumar durante su utilización.

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P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

Español:

EN CASO DE INGESTIÓN: Llamar inmediatamente a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.

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P405

Deutsch:

Unter Verschluss aufbewahren.

English:

Store locked up.

Français:

Garder sous clef.

Italiano:

Conservare sotto chiave.

Español:

Guardar bajo llave.