AEBSF-HClresearch grade
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C8H10FNO2S·HCl • Mr 239.7 • CAS [30827-99-7]
Irreversible inhibitor of thrombin and other serine proteases (e.g. chymotrypsin, kallikrein, plasmin, proteinase K, trypsin). Inhibits by acylation of the active site of the enzyme. AEBSF is water-soluble and much less toxic than PMSF and DFP. Aqueous solutions are stable between pH 5 - 6; limited stability above pH 7.5.
Assay (HPLC)
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min. 98.0 %
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References:
- Walsmann, P. et al. (1972) Acta biol. med. germ. 28, 577-585
- Marwardt, F. et al. (1973) Thrombosis Res. 2, 343-348
- Taylor, J.A. et al. (1995) Immunology 86, 629-635
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DANGER |
Hazard Statements | H314 |
Precautions | P264 - P280 |
Reaction | P301 +P330 +P331 - P303 +P361 +P353 - P304 +P340 - P305 +P351 +P338 |
GGVSE/ADR: 8 II UN3261 • IATA: 8 II UN3261 • WGK: 1 • HS: 29214900
Storage Temperature: +2 °C to +8 °C