Erythromycin baseresearch grade, Ph. Eur.

C37H67NO13Mr 733.92CAS [114-07-8]

Mixture of macrolide-glycoside antibiotics produced by a strain of Streptomyces erythreus, the main component being Erythromycin A. Broad- spectrum antibiotic. Inhibitor of protein biosynthesis (2,3): inhibits peptide elongation on the ribosome by binding close to the peptidyl transferase center and blocking the peptide exit tunnel in the large ribosomal subunit (4,5).

Assay (HPLC)
(Sum of Erythromycin A, B, and C)

93.0 - 102.0 %


References:
  1. Tanaka, K. et al. (1972) Mol. Genet. 114, 9-30
  2. Jagendorf, A.T. & Michaels, A. (1990) . Plant Science 71, 137-45
  3. Bogorad, L. (2003) Photosynth. Res. 76, 13-33
  4. Lovmar, M. et al. (2004) J. Biol. Chem. 279, 53506-15
  5. Lovmar, M. et al. (2006) J. Biol. Chem. 281, 6742-50
  6. Kohanski, M.A. et al. (2007) Cell 130, 797-810

EINECS: 204-040-1WGK: 1HS: 29415000
Storage Temperature: +15 °C to +30 °C

Cat.No.
Size
EUR
21208.02
5 g
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