N-Dodecyl-β-D-Maltoside, LAAnagrade
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(N-Dodecyl-β-D-Maltopyranoside, Lauryl Maltoside, Dodecyl 4-O-α-D-Glucopyranosyl-β-D-Glucopyranoside, DDM, LM)
C24H46O11 • Mr 510,6 • CAS [69227-93-6]
C24H46O11 • Mr 510,6 • CAS [69227-93-6]
CMC (H2O) ca. 0.17 mM, Na (H2O) 78 - 149
One of the most used detergents for extraction, purification and
crystallization of membrane proteins
N-Dodecyl-β-D-Maltoside
(DDM)/N-Decyl-β-D-Maltoside (DM) has been used in the extraction of over 80 %
of eukaryotic membrane protein structures.
DDM with and without cholesterol
is a good detergent choice for LCP experiments.
|
Purity (HPLC)
Content α anomer (HPLC) Content dodecanol (HPLC) Solubility in H2O (0 - 5 °C) |
≥ 99 %
< 0.2 % < 0.005 % ≥ 20 % |
References:
- Brown, G. M. et al. (1970) Canadian J. Chem. 48, 2525-2531
- VanAken, T. et al. (1986) Methods Enzymol. 125, 27-35
- Strop, P. & Brunger, A. T. (2005) Protein Sci. 14, 2207-2211
HS: 29400000
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