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Pepstatin A

(Isovaleryl-L-valyl-L-valyl-4-amino-3-hydroxy-6-methylheptanoyl-L- alanyl-4-amino-3-hydroxy-6-methylheptanoic acid; X-Val-Val-statyl-Ala-statin)
C34H63N5O9 • Mr 685.9 • CAS [26305-03-3]

Inhibitor of aspartic proteases, e.g. pepsin, renin, cathepsin D (1 - 3) and of retroviral proteases (4 - 7).

Assay (HPLC)
min. 98.0 %


References:
  1. Umezawa, H. (1976) Meth. Enzymol. 45, 689-93
  2. McCaffrey, G. & Jamieson, J.C. (1993) Comp. Biochem. Physiol. 104, 91-4
  3. Bailly, E. et al. (1991) Exp. Parasitol. 72, 278-84
  4. Baum, E.Z. et al. (1990) Proc. Natl. Acad. Sci. USA 87, 10023-7
  5. Grinde, B. et al. (1989) AIDS Res. Hum. Retroviruses 5, 269-74
  6. von der Helm, K. et al. (1989) FEBS Lett. 247, 349-52
  7. Katoh, I. et al. (1987) Nature 329, 654-6

EINECS: 247-600-0 • HS: 29241900
Storage Temperature: +2 °C to +8 °C

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52682.02
5 mg
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52682.03
25 mg
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