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Digitoninanalytical grade, USP

(Digitin)
C56H92O29 • Mr 1229.34 • CAS [11024-24-1]

Digitonin is a naturally occurring surfactant especially useful for receptor solubilization. The detergent is frequently applied as hemolysis reagent and for permeabilization of certain types of cells e.g. blood platelets, hepatocytes, yeast or tumor cells. Also used for the estimation of cholesterol.
CMC (25 °C) 0.67 - 0.73 mM, Na (25 °C) 60, HLB 0.4


References:
  1. Scallen, D.J. & Dietert, S.E. (1969) J. Cell Biol. 40, 802- 13
  2. Grigoriadis, D.E. et al. (1989) Endocrinology 125, 3068-77
  3. Hermann, P. et al. (1988) Photosynthetica 22, 411-22
  4. Boschmann, M. et al. (1989) Biomed. Biochim. Acta 48, 645-52
  5. Mooney, R.A. (1988) in Meth. Enzymol. 159, (Corbin, J.D. & Johnson, R.A., Eds.) 193-202, Academic Press, Inc.
DANGER
Hazard Statements H301 - H311 - H331
Precautions P280
Reaction P301 +P310 - P302 +P352 - P304 +P340 - P311 - P330

GGVSE/ADR: 6.1 II UN2811 • IATA: 6.1 II UN2811 • EINECS: 234-255-6 • WGK: 3L • HS: 29389010
Storage Temperature: +15 °C to +30 °C

Cat.No.
Size
EUR
19550.02
1 g
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H301

Deutsch:

Giftig bei Verschlucken.

English:

Toxic if swallowed.

Français:

Toxique en cas d'ingestion.

Italiano:

Tossico se ingerito.

Español:

Tóxico en caso de ingestión.

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H311

Deutsch:

Giftig bei Hautkontakt.

English:

Toxic in contact with skin.

Français:

Toxique par contact cutané.

Italiano:

Tossico per contatto con la pelle.

Español:

Tóxico en contacto con la piel.

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H331

Deutsch:

Giftig bei Einatmen.

English:

Toxic if inhaled.

Français:

Toxique par inhalation.

Italiano:

Tossico se inalato.

Español:

Tóxico en caso de inhalación.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P301 +P310

Deutsch:

BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Français:

EN CAS D’INGESTION: appeler immédiatement un CENTRE ANTIPOISON ou un médecin.

Italiano:

IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI o un medico

Español:

EN CASO DE INGESTIÓN: Llamar inmediatamente a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.

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P302 +P352

Deutsch:

BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.

English:

IF ON SKIN: Wash with plenty of soap and water.

Français:

EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.

Italiano:

IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.

Español:

EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.

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P304 +P340

Deutsch:

BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

English:

IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Français:

EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

Italiano:

IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

Español:

EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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P311

Deutsch:

GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

Call a POISON CENTER or doctor/physician.

Français:

Appeler un CENTRE ANTIPOISON ou un médecin.

Italiano:

Contattare un CENTRO ANTIVELENI o un medico.

Español:

Llamar a un CENTRO DE INFORMACION TOXICOLOGICA o a un médico.

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P330

Deutsch:

Mund ausspülen.

English:

Rinse mouth.

Français:

Rincer la bouche.

Italiano:

Sciacquare la bocca.

Español:

Enjuagarse la boca.