Guanidine·thiocyanatemolecular biology grade

CH5N3·HSCNMr 118.2CAS [593-84-0]

Guanidine thiocyanate (GTC) is a chaotropic agent and strong denaturant. It solubilizes proteins by interfering with the hydrogen bonds and intramolecular interactions resulting in disintegration of cellular structures. GTC is involved in separation of ribosomal ribonucleic acid (rRNA) from ribosomes and denatures RNase and can therefore be used for extraction of RNA.

Assay
MP

min. 98.5 %
115 - 122 °C

DANGER
Hazard Statements H302 - H312 - H314 - H332 - H412
EUH EUH 032
Precautions P273 - P280
Reaction P301 +P312 - P302 +P352 - P304 +P340 - P305 +P351 +P338

EG-Index: 615-004-00-3GGVSE/ADR: 8 III UN1759IATA: 8 III UN1759EINECS: 209-812-1WGK: 2LHS: 29252900
Storage Temperature: +15 °C to +30 °C

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H302

Deutsch:

Gesundheitsschädlich bei Verschlucken.

English:

Harmful if swallowed.

Français:

Nocif en cas d'ingestion.

Italiano:

Nocivo se ingerito.

Español:

Nocivo en caso de ingestión.

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H312

Deutsch:

Gesundheitsschädlich bei Hautkontakt.

English:

Harmful in contact with skin.

Français:

Nocif par contact cutané.

Italiano:

Nocivo per contatto con la pelle.

Español:

Nocivo en contacto con la piel.

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H314

Deutsch:

Verursacht schwere Verätzungen der Haut und schwere Augenschäden.

English:

Causes severe skin burns and eye damage.

Français:

Provoque des brûlures de la peau et des lésions oculaires graves.

Italiano:

Provoca gravi ustioni cutanee e gravi lesioni oculari.

Español:

Provoca quemaduras graves en la piel y lesiones oculares graves.

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H332

Deutsch:

Gesundheitsschädlich bei Einatmen.

English:

Harmful if inhaled.

Français:

Nocif par inhalation.

Italiano:

Nocivo se inalato.

Español:

Nocivo en caso de inhalación.

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H412

Deutsch:

Schädlich für Wasserorganismen, mit langfristiger Wirkung.

English:

Harmful to aquatic life with long lasting effects.

Français:

Nocif pour les organismes aquatiques, entraîne des effets néfastes à long terme.

Italiano:

Nocivo per gli organismi acquatici con effetti di lunga durata.

Español:

Nocivo para los organismos acuáticos, con efectos nocivos duraderos.

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EUH 032

Deutsch:

Entwickelt bei Berührung mit Säure sehr giftige Gase.

English:

Contact with acids liberates very toxic gas.

Français:

Au contact d'un acide, dégage un gaz très toxique.

Italiano:

A contatto con acidi libera gas molto tossici.

Español:

En contacto con ácidos libera gases muy tóxicos.

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P273

Deutsch:

Freisetzung in die Umwelt vermeiden.

English:

Avoid release to the environment.

Français:

Éviter le rejet dans l’environnement.

Italiano:

Non disperdere nell’ambiente.

Español:

Evitar su liberación al medio ambiente.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P301 +P312

Deutsch:

BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

English:

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Français:

EN CAS D’INGESTION: appeler un CENTRE ANTIPOISON ou un médecin en cas de malaise.

Italiano:

IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI o un medico.

Español:

EN CASO DE INGESTIÓN: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico si se encuentra mal.

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P302 +P352

Deutsch:

BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.

English:

IF ON SKIN: Wash with plenty of soap and water.

Français:

EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.

Italiano:

IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.

Español:

EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.

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P304 +P340

Deutsch:

BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

English:

IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Français:

EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

Italiano:

IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

Español:

EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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P305 +P351 +P338

Deutsch:

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

English:

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Français:

EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer

Italiano:

IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

Español:

EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.