Kanamycin sulfatemolecular biology grade, Ph. Eur.

C18H36N4O11·H2SO4·H2OMr 600.6CAS [5965-95-7]

Aminoglycoside antibiotic, inhibitor of protein biosynthesis. It is active against gram negative and gram positive bacteria. Main component is Kanamycin A. Suitable for prevention of bacterial contamination in cell culture. Used in molecular biology for the selection of resistant bacteria.
Activity: min. 750 U/mg. Easily soluble in water.
Stock solution: 10 mg/ml in H2O, working solution: 100 µg/ml.


References:
  1. Pestka, S. (1971) Annu. Rev. Microbiol. 25, 487-562
  2. Mays, D. et al. (1976) J. Chromatogr. 120, 193-202
  3. Cox, D. et al. (1977) in: Sammes, P.G. (ed.) Topics in Antibiotic Chemistry, vol. 3, Chichester, Horwood pp. 1-90
  4. Lancini, G. & Parenti, F. (1982) Antibiotics: Springer, New York
  5. Nakashima, K. et al. (1999) . J. Biol. Chem. 274, 27786-92
  6. Vetting, M.W. et al. (2002) Nature Struct. Biol. 9, 653-8
  7. Lambert, C. et al. (2003) Environm. Biol. 5, 127-32
  8. Kataoka, T. et al. (2004) Plant Physiol. 136, 4198-204
DANGER
Hazard Statements H360
Precautions P201 - P202 - P280
Reaction P308 +P313
Storage P405

WGK: 1HS: 29419000
Storage Temperature: +2 °C to +8 °C

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Size
EUR
26899.01
1 g
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26899.02
5 g
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26899.03
25 g
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H360

Deutsch:

Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen <konkrete Wirkung angeben, sofern bekannt> <Expositionsweg angeben, sofern schlüssig belegt ist, dass die Gefahr bei keinem anderen Expositionsweg besteht>.

English:

May damage fertility or the unborn child <state specific effect if known > <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

Français:

Peut nuire à la fertilité ou au foetus <indiquer l'effet spécifique s'il est connu> <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger>.

Italiano:

Può nuocere alla fertilità o al feto <indicare l'effetto specifico, se noto><indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo>.

Español:

Puede perjudicar la fertilidad o dañar al feto <indíquese el efecto específico si se conoce><indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía>.

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P201

Deutsch:

Vor Gebrauch besondere Anweisungen einholen.

English:

Obtain special instructions before use.

Français:

Se procurer les instructions avant utilisation.

Italiano:

Procurarsi istruzioni specifiche prima dell’uso.

Español:

Pedir instrucciones especiales antes del uso.

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P202

Deutsch:

Vor Gebrauch sämtliche Sicherheitsratschläge lesen und verstehen.

English:

Do not handle until all safety precautions have been read and understood.

Français:

Ne pas manipuler avant d’avoir lu et compris toutes les précautions de sécurité.

Italiano:

Non manipolare prima di avere letto e compreso tutte le avvertenze.

Español:

No manipular la sustancia antes de haber leído y comprendido todas las instrucciones de seguridad.

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P280

Deutsch:

Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

English:

Wear protective gloves/protective clothing/eye protection/face protection.

Français:

Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

Italiano:

Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

Español:

Llevar guantes/prendas/gafas/máscara de protección.

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P308 +P313

Deutsch:

BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

English:

IF exposed or concerned: Get medical advice/attention.

Français:

EN CAS d’exposition prouvée ou suspectée: consulter un médecin.

Italiano:

IN CASO di esposizione o di possibile esposizione, consultare un medico.

Español:

EN CASO DE exposición manifiesta o presunta: Consultar a un médico.

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P405

Deutsch:

Unter Verschluss aufbewahren.

English:

Store locked up.

Français:

Garder sous clef.

Italiano:

Conservare sotto chiave.

Español:

Guardar bajo llave.