Approved quality for use with in-gel digestion and mass spectrometric analysis.
Lysyl Endopeptidase (LysC), originally isolated from the soil bacterium discovered by Masaki, et al. cleaves specifically the peptide bonds at the carboxy-terminal side of Lysine residues and S-aminoethylcysteine residues with a high degree of specificity, making it a valuable tool for protein sequence analysis and for proteome research. An added feature of Lysyl Endopeptidase is its ability to retain complete activity after incubation in 4 M urea or in 0.1 % SDS solution for up to 6 hours at 30 °C.