Proteinase K, recombinant, min. 35 mAnson-U/mglyophil., NGS grade

EC 3.4.21.14Mr 28.900,00 CAS [39450-01-6]

A recombinant proteinase K from Tritirachium album expressed in Pichia pastoris.

Subtilisin-related serine protease with a very high specific activity and a broad spectrum of action. It is widely used for digestion of proteins, including DNases and RNases during nucleic acid preparations without compromising the integrity of the isolated DNA or RNA.

An extra purification step results in 2.5-fold increased solubility, increased specific activity and very low DNA content compared to other comercially available recombinant proteinase K preparations. Therefore it is especially suitable for methods demanding highest quality like Next Generation Sequencing (NGS).

  • Free of endonucleases, exonucleases and ribonucleases
  • Solubility in water: ≥ 50 mg/ml
  • DNA: ≤0.1 pg/mg enzyme


  • DANGER
    Hazard Statements H315 - H319 - H334 - H335
    Precautions P280 - P284
    Reaction P302 +P352 - P304 +P340 - P305 +P351 +P338 - P342 +P311

    EINECS: 254-457-8WGK: 1HS: 35079090
    Storage Temperature: -15 °C to -25 °C

    Cat.No.
    Size
    EUR
    33757.01
    25 mg
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    33757.02
    100 mg
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    33757.03
    500 mg
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    H315

    Deutsch:

    Verursacht Hautreizungen.

    English:

    Causes skin irritation.

    Français:

    Provoque une irritation cutanée.

    Italiano:

    Provoca irritazione cutanea.

    Español:

    Provoca irritación cutánea.

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    H319

    Deutsch:

    Verursacht schwere Augenreizung.

    English:

    Causes serious eye irritation.

    Français:

    Provoque une sévère irritation des yeux.

    Italiano:

    Provoca grave irritazione oculare.

    Español:

    Provoca irritación ocular grave.

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    H334

    Deutsch:

    Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen.

    English:

    May cause allergy or asthma symptoms or breathing difficulties if inhaled.

    Français:

    Peut provoquer des symptômes allergiques ou d'asthme ou des difficultés respiratoires par inhalation.

    Italiano:

    Può provocare sintomi allergici o asmatici o difficoltà respiratorie se inalato.

    Español:

    Puede provocar síntomas de alergia o asma o dificultades respiratorias en caso de inhalación.

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    H335

    Deutsch:

    Kann die Atemwege reizen.

    English:

    May cause respiratory irritation.

    Français:

    Peut irriter les voies respiratoires.

    Italiano:

    Può irritare le vie respiratorie.

    Español:

    Puede irritar las vías respiratorias.

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    P280

    Deutsch:

    Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

    English:

    Wear protective gloves/protective clothing/eye protection/face protection.

    Français:

    Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.

    Italiano:

    Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.

    Español:

    Llevar guantes/prendas/gafas/máscara de protección.

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    P284

    Deutsch:

    Atemschutz tragen.

    English:

    Wear respiratory protection.

    Français:

    Porter un équipement de protection respiratoire.

    Italiano:

    Utilizzare un apparecchio respiratorio.

    Español:

    Llevar equipo de protección respiratoria.

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    P302 +P352

    Deutsch:

    BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.

    English:

    IF ON SKIN: Wash with plenty of soap and water.

    Français:

    EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.

    Italiano:

    IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.

    Español:

    EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.

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    P304 +P340

    Deutsch:

    BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das Atmen erleichtert.

    English:

    IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.

    Français:

    EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.

    Italiano:

    IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.

    Español:

    EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.

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    P305 +P351 +P338

    Deutsch:

    BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

    English:

    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Français:

    EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer

    Italiano:

    IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.

    Español:

    EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.

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    P342 +P311

    Deutsch:

    Bei Symptomen der Atemwege: GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

    English:

    If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.

    Français:

    En cas de symptômes respiratoires: appeler un CENTRE ANTIPOISON ou un médecin.

    Italiano:

    In caso di sintomi respiratori: contattare un CENTRO ANTIVELENI o un medico.

    Español:

    En caso de síntomas respiratorios: Llamar a un CENTRO DE INFORMACIÓN TOXICOLÓGICA o a un médico.