Bacitracinresearch grade, USP

(Bacidrin, Ginebatine)
Mr ca. 1422 CAS [1405-87-4]

Bacitracin is a polypeptide antibiotic recovered from certain strains of B. spizizenii (former B. subtilis) and B. licheniformis. It inhibits cell wall biosynthesis in gram-positive bacteria and Neisseria by inhibition of peptidoglycan synthesis. Bacitracin may as well be used as protease inhibitor.
Min. 60 000 IU/g. Main component Bacitracin A. Bactericidal activity requires divalent cations like Zn2+ (1). The concentration of stock solution is 100 - 1000 mg/ml in H2O or ethanol, stored at -20 °C. The working concentration is 0.1 - 1 mg/ml (0.07 - 0.7 mM). Bacitracin is very stable in a pH range of 4 - 5, but is rapidly inactivated in pH of over 5 at room temperature.




References:
  1. Scogin, D. et al. (1980) Biochemistry 19, 3348-52

EINECS: 215-786-2WGK: 2HS: 29419000
Storage Temperature: +2 °C to +8 °C

Cat.No.
Size
EUR
14419.02
25 g
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