N-Dodecyl-β-D-MaltosideAnagrade
(N-Dodecyl-β-D-Maltopyranoside, Lauryl Maltoside, Dodecyl 4-O-α-D-Glucopyranosyl-β-D-Glucopyranoside, DDM, LM)
C24H46O11
• Mr
510,6
• CAS [69227-93-6]
CMC (H2O) ca. 0.17 mM, Na (H2O) 78 - 149
One of the
most used detergents used for extraction, purification and crystallization of
membrane proteins
N-Dodecyl-β-D-Maltoside (DDM)/N-Decyl-β-D-Maltoside (DM)
has been used in the extraction of over 80 % of eukaryotic membrane protein
structures.
DDM with and without cholesterol is a good detergent choice for
LCP experiments.
Purity (HPLC)
Content α anomer (HPLC)
Content dodecanol (HPLC)
Solubility
in H2O (0 - 5 °C)
|
≥ 99 %
< 2 %
< 0.005 %
≥ 20 %
|
References:
-
Brown, G. M., Dubreuil, P. et al. (1970) Canadian J. Chem. 48, 2525-2531
- VanAken, T. et al. (1986) Methods Enzymol. 125, 27-35
-
Strop, P. & Brunger, A. T. (2005) Protein Sci. 14, 2207-2211
HS: 29400000
*Please use the inquiry form in the right column.
Material Safety Datasheets
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H315
Deutsch:
Verursacht Hautreizungen.
English:
Causes skin irritation.
Français:
Provoque une irritation cutanée.
Italiano:
Provoca irritazione cutanea.
Español:
Provoca irritación cutánea.
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H319
Deutsch:
Verursacht schwere Augenreizung.
English:
Causes serious eye irritation.
Français:
Provoque une sévère irritation des yeux.
Italiano:
Provoca grave irritazione oculare.
Español:
Provoca irritación ocular grave.
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H335
Deutsch:
Kann die Atemwege reizen.
English:
May cause respiratory irritation.
Français:
Peut irriter les voies respiratoires.
Italiano:
Può irritare le vie respiratorie.
Español:
Puede irritar las vías respiratorias.
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P260
Deutsch:
Staub/Rauch/Gas/Nebel/Dampf/Aerosol nicht einatmen.
English:
Do not breathe dust/fume/gas/mist/vapours/spray.
Français:
Ne pas respirer les poussières/fumées/gaz/brouillards/vapeurs/aérosols.
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Non respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
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P280
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Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
English:
Wear protective gloves/protective clothing/eye protection/face protection.
Français:
Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.
Italiano:
Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
Español:
Llevar guantes/prendas/gafas/máscara de protección.
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P302 +P352
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BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.
English:
IF ON SKIN: Wash with plenty of soap and water.
Français:
EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.
Italiano:
IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.
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EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.
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P304 +P340
Deutsch:
BEI EINATMEN: An die frische Luft bringen und in einer Position ruhigstellen, die das
Atmen erleichtert.
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IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Français:
EN CAS D’INHALATION: transporter la victime à l’extérieur et la maintenir au repos dans une position où elle peut confortablement respirer.
Italiano:
IN CASO DI INALAZIONE: trasportare l'infortunato all’aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
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EN CASO DE INHALACIÓN: Transportar a la víctima al exterior y mantenerla en reposo en una posición confortable para respirar.
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P305 +P351 +P338
Deutsch:
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen.
Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
English:
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Français:
EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer
Italiano:
IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
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EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.
