Octyl Glucose Neopentyl Glycol
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C27H52O12 • Mr 568,69 • CAS [1257853-32-9]
CMC (H2O) ca. 1.02 mM
Octyl Glucose Neopentyl Glycol (OGNG) is an alternative to
N-Octyl-β-D-Glucoside (OG) that could improve protein structural stability and
increase the likelihood of crystallization.
Architecturally, the difference
lies where the carbon attaches to the ether linkage. The design converts the
carbon from a standard, secondary bonding configuration to a quaternary
configuration with two head groups and two alkyl chains bonded to it.
As with other detergents, the detergent performance of Octyl Glucose Neopentyl Glycol will vary with each membrane protein. To see which works the best for your research, we recommend you run parallel experiments with conventional OG and Anatrace OGNG. Simply use the same concentration and protocol, and then compare the results.
Purity (HPLC) Content anomers (HPLC) Solubility in H2O (20 °C) |
≥ 98 % ≤ 0.4 % ≥ 20 % |
References:
- Chae, Pil Seok et al. (2010) Nature Methods. 7 (12), 1003-1008
HS: 34024900