Novobiocin·Na-saltresearch grade
C31H35N2O11·Na • Mr 634.6 • CAS [1476-53-5]
Coumarin-glycoside antibiotic. Inhibitor of bacterial DNA gyrase (1).
Mechanism of action (2). Antagonist of heat shock protein 90 (Hsp90) (3, 4, 5).
Assay (HPLC)
MP
|
min. 98.0 %
210 - 220 °C
|
References:
- Cozzarelli, N.R. (1980) Science 207, 953-60
- Staudenbauer, W.L. (1975) J. Mol. Biol. 96, 201-5
-
Marcu, M.G. et al. (2000) J. Natl. Cancer Inst. 92, 242-8
-
Marcu, M.G. et al. (2000) J. Biol. Chem. 275, 37181-6
-
Sreedhar, A.S. et al. (2003) J. Biol. Chem. 278, 35231-40
EINECS: 216-023-6 •
WGK: 1 •
HS: 29419000
Storage Temperature: +2 °C to +8 °C
*Please use the inquiry form in the right column.
Certificates of Analysis
(Lot.-no. - release date)
Material Safety Datasheets
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Electrophoresis by SERVA - Catalog
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In detail you will find the following new products in catalog 2022:
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New glycosidases such as Endo F3, Endo S and Sialidase |
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Blotting kits to match the "Easy Peel" 2D HPE™ gels for blotting horizontal 2D gels |
| • |
New protein standards, e.g. SERVA Triple Color Protein Standard I and the SERVA Fluo-610 Protein Standard I, pre-stained for direct fluorescence detection |
| • |
BlueVertical™ PRiME™ blot module and gel casting stand for SERVA's BV-104 electrophoresis tank |
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he albumin portfolio has been expanded with the "Albumin bovine Fraction V, protease- free, low IgG" |
| • |
Ready-to-use CL HRP Western Blotting Substrates SERVALight "PreMix" |
SERVA Catalog 2023.pdf
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H317
Deutsch:
Kann allergische Hautreaktionen verursachen.
English:
May cause an allergic skin reaction.
Français:
Peut provoquer une allergie cutanée.
Italiano:
Può provocare una reazione allergica cutanea.
Español:
Puede provocar una reacción alérgica en la piel.
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H319
Deutsch:
Verursacht schwere Augenreizung.
English:
Causes serious eye irritation.
Français:
Provoque une sévère irritation des yeux.
Italiano:
Provoca grave irritazione oculare.
Español:
Provoca irritación ocular grave.
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P261
Deutsch:
Einatmen von Staub/Rauch/Gas/Nebel/Dampf/Aerosol vermeiden.
English:
Avoid breathing dust/fume/gas/mist/vapours/spray.
Français:
Éviter de respirer les poussières/fumées/gaz/brouillards/vapeurs/aérosols.
Italiano:
Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
Español:
Evitar respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.
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P280
Deutsch:
Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.
English:
Wear protective gloves/protective clothing/eye protection/face protection.
Français:
Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/du visage.
Italiano:
Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
Español:
Llevar guantes/prendas/gafas/máscara de protección.
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P302 +P352
Deutsch:
BEI KONTAKT MIT DER HAUT: Mit viel Wasser und Seife waschen.
English:
IF ON SKIN: Wash with plenty of soap and water.
Français:
EN CAS DE CONTACT AVEC LA PEAU: laver abondamment à l’eau et au savon.
Italiano:
IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua e sapone.
Español:
EN CASO DE CONTACTO CON LA PIEL: Lavar con agua y jabón abundantes.
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P305 +P351 +P338
Deutsch:
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen.
Vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
English:
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Français:
EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l’eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer
Italiano:
IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
Español:
EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.
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P333 +P313
Deutsch:
Bei Hautreizung oder -ausschlag: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
English:
If skin irritation or rash occurs: Get medical advice/attention.
Français:
En cas d’irritation ou d'éruption cutanée: consulter un médecin.
Italiano:
In caso di irritazione o eruzione della pelle: consultare un medico.
Español:
En caso de irritación o erupción cutánea: Consultar a un médico.
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P337 +P313
Deutsch:
Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
English:
If eye irritation persists: Get medical advice/attention.
Français:
Si l’irritation oculaire persiste: consulter un médecin.
Italiano:
Se l’irritazione degli occhi persiste, consultare un medico.
Español:
Si persiste la irritación ocular: Consultar a un médico.
