Nystatin min. 4 400 units/mgresearch grade, Ph. Eur.

(Fungicidin, Mycostatin)
C47H75NO17·2H2OMr 926.13CAS [1400-61-9]

Polyene macrolide antibiotic isolated from Streptomyces noursei. Used in animal and plant cell cultures against fungi and yeasts. Forms complexes with ergosterol in the fungal cell membrane resulting in the formation of pores and loss of ions and small molecules.


References:
  1. Chong, C.N. et al. (1970) Tetrahedron Lett. 59, 5145-8
  2. Coutinho, A. et al. (2004). Biophys. J. 87, 3264-76
  3. Leifert, C. et al. (1991) J. Microbiol. Biotechnol. 7, 452-69
  4. Constabel, F. & Shyluk, J.P. (1994): Plant Cell and Tissue Culture, eds. I.K. Vasil a. T.A. Thorpe; pp 3-15. Springer Netherlands
  5. Banu, K.S. et al. (2001) Endocrine Pathol. 12, 315-27
  6. Wang, A. et al. (2005) Appl. Environ. Microbiol. 71, 8397-401
  7. Funkenstein, B. et al. (2006) Tissue and Cell 38, 399-415

EINECS: 215-749-0HS: 29419000
Storage Temperature: +2 °C to +8 °C

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