Rifampicinresearch grade
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C43H58N4O12 • Mr 822.96 • CAS [13292-46-1]
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Semisynthetic derivative of rifamycin SV which is produced from certain strains of Amycolatopsis mediterranei. Belongs to the group of ansamycin antibiotics. Inhibitor of DNA-dependent RNA-polymerase. Specifically inhibits the initiation step of RNA synthesis.
Assay |
98.0 - 102.0 % |
References:
- Meilhac, M. et al. (1972) Eur. J. Biochem. 28, 291-300
- Ohta, S. et al. (1990) . Plant Cell Physiol. 31, 805-13
- Dreher, J. et al. (1991), Molecular Microbiology, 5 (12), 3025-3034
- Vilchez, S. et al. (2000) J. Bacteriol. 182, 91-9
- Schwalb, C. et al. (2003) Biochemistry 42, 9491-7
- Freiberg, C. et al. (2004) Current Opinion in Microbiology 7, 451-9
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WARNING |
Hazard Statements | H302 - H315 - H319 - H335 |
Precautions | P261 - P280 |
Reaction | P301 +P312 - P302 +P352 - P304 +P340 - P305 +P351 +P338 |
EINECS: 236-312-0 • WGK: 1 • HS: 29419000
Storage Temperature: +2 °C to +8 °C