ASB-14
Synthetic detergent with a C14 alkyl tail. It is useful for solubilizing proteins for 2D-analysis. ASB-14 shows better protein solubilization properties than CHAPS, by which the identification of previously undetected membrane proteins was enabled.
Synonym: Amidosulfobetaine-14; 3-[N,N-Dimethyl-(3-myristoylaminopropyl)-ammonio]-propanesulfonate; 3-[N,N-Dimethyl-N-(3-myristamidopropyl)-ammonio)]-propane-1-sulfonate.
CAS registry number: [216667-08-2]
Molecular formula: C22H46N2O4S
Relative molecular mass (Mr): 434.7
Classification: Zwitterionic surfactant
Critical micellar concentration (CMC): 8 mM
Bibliography
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