Synperonic® F 68
Synperonic F-68 is a polyoxyethylene-polyoxypropylene copolymer with important biotechnological and medical applications.
The non-ionic surfactant Synperonic F-68 can be effectively used in cell culture to protect microorganisms, animal and plant cells against mechanical damage. Corresponding effects have been observed in the cultivation of cells from insects, yeasts, fibroblasts and melano¬mas. In addition, the surfactant enhances the growth of animal and plant cells by increasing the nutrient uptake.
Synperonic F-68 is a valuable supplement in plant cell culture for exploitation of membrane effects in genetic manipulations involving protoplasts.
Due to its excellent emulsifying properties, Synperonic F68 is very well suited for investigations of water insoluble active ingredients in biotechnology and pharmacology.
Emulsions of perfluorochemicals with Synperonic F-68 are of considerable medical impor-tance: they are being evaluated as adjuncts to enhance oxygenation of ischaemic tissues. isolated organs and tumors.
Synperonic is a registered trademark of CRODA International Plc.
Synonyms: Pluronic PE 6800, Pluronic F-68, Poloxamer 188
CAS registry number : [9003-11-6]
Relative molecular mass (Mr): appox. 8300
Classification: non-ionic surfactant
Literature specification :
• Critical micellar concentration (CMC) : 0.04 mM
• Hydrophilic-lipophilic balance (HLB) : 29
Cell Culture Techniques
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